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Delineation of biological and molecular mechanisms underlying the diverse anticancer activities of mycophenolic acid

Background: Mycophenolate mofetil (MMF), the prodrug of mycophenolic acid (MPA) which has been widely used for the prevention of acute graft rejection, is a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH) that is up-regulated in many tumors and potentially a target for cancer therapy...

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Autori principali: Dun, Boying, Xu, Heng, Sharma, Ashok, Liu, Haitao, Yu, Hongfang, Yi, Bing, Liu, Xiaoxin, He, Mingfang, Zeng, Lingwen, She, Jin-Xiong
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843268/
https://ncbi.nlm.nih.gov/pubmed/24294374
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