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Optimization of the route of platinum drugs administration to optimize the concomitant treatment with radiotherapy for glioblastoma implanted in the Fischer rat brain

Treatment of glioblastoma with platinum compounds modestly improves progression-free survival and may cause toxic effects which prevent use at higher dose that would otherwise improve the antineoplastic effect. To reduce toxicity, we propose to encapsulate the platinum drug in a liposome. We have al...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Charest, Gabriel, Sanche, Léon, Fortin, David, Mathieu, David, Paquette, Benoit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829823/
https://ncbi.nlm.nih.gov/pubmed/24026531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-013-1238-8
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