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Stereo-selective neuroprotection against stroke with vitamin A derivatives
In this study we evaluated the neuroprotective potential of vitamin A (all-trans retinol), and its geometric isomers, all-trans retinoic acid and 9-cis retinoic acid, in a focal model of ischemia. A 60 minute middle cerebral artery occlusion in C57 mice resulted in over 50% hemispheric infarction. V...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829682/ https://ncbi.nlm.nih.gov/pubmed/18824156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.09.020 |
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