Multivoxel (1)H MR spectroscopy is superior to contrast-enhanced MRI for response assessment after anti-angiogenic treatment of orthotopic human glioma xenografts and provides handles for metabolic targeting

BACKGROUND: Anti-angiogenic treatment of glioblastoma characteristically results in therapy resistance and tumor progression via diffuse infiltration. Monitoring tumor progression in these patients is thwarted because therapy results in tumor invisibility in contrast-enhanced (CE) MRI. To address th...

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Main Authors: Hamans, Bob, Navis, Anna Catharina, Wright, Alan, Wesseling, Pieter, Heerschap, Arend, Leenders, William
格式: Artigo
語言:Inglês
出版: Oxford University Press 2013
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829596/
https://ncbi.nlm.nih.gov/pubmed/24158109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not129
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