Effects of Dual Targeting of Tumor Cells and Stroma in Human Glioblastoma Xenografts with a Tyrosine Kinase Inhibitor against c-MET and VEGFR2

Anti-angiogenic treatment of glioblastoma with Vascular Endothelial Growth Factor (VEGF)- or VEGF Receptor 2 (VEGFR2) inhibitors normalizes tumor vessels, resulting in a profound radiologic response and improved quality of life. This approach however does not halt tumor progression by diffuse infilt...

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מידע ביבליוגרפי
Main Authors: Navis, Anna C., Bourgonje, Annika, Wesseling, Pieter, Wright, Alan, Hendriks, Wiljan, Verrijp, Kiek, van der Laak, Jeroen A. W. M., Heerschap, Arend, Leenders, William P. J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587584/
https://ncbi.nlm.nih.gov/pubmed/23484006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058262
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