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Genetic control of cobalamin binding in normal and mutant cells: Assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1

When extracts prepared from cultured human or rodent fibroblasts grown in medium containing [(57)Co]cobalamin were analyzed by polyacrylamide gel electrophoresis, most of the intracellular radioactivity migrated with the activity of the cobalamin-dependent enzyme 5-methyltetrahydrofolate:L-homocyste...

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Bibliografiske detaljer
Main Authors: Mellman, Ira S., Lin, Pin-Fang, Ruddle, Frank H., Rosenberg, Leon E.
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC382948/
https://ncbi.nlm.nih.gov/pubmed/284356
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