The Paired-box Homeodomain Transcription Factor Pax6 Binds to the Upstream Region of the TRAP Gene Promoter and Suppresses Receptor Activator of NF-κB Ligand (RANKL)-induced Osteoclast Differentiation

Osteoclast formation is regulated by balancing between the receptor activator of nuclear factor-κB ligand (RANKL) expressed in osteoblasts and extracellular negative regulatory cytokines such as interferon-γ (IFN-γ) and interferon-β (IFN-β), which can suppress excessive bone destruction. However, re...

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Autori principali: Kogawa, Masakazu, Hisatake, Koji, Atkins, Gerald J., Findlay, David M., Enoki, Yuichiro, Sato, Tsuyoshi, Gray, Peter C., Kanesaki-Yatsuka, Yukiko, Anderson, Paul H., Wada, Seiki, Kato, Naoki, Fukuda, Aya, Katayama, Shigehiro, Tsujimoto, Masafumi, Yoda, Tetsuya, Suda, Tatsuo, Okazaki, Yasushi, Matsumoto, Masahito
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829441/
https://ncbi.nlm.nih.gov/pubmed/23990468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.461848
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