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The Functional Interaction of Mitochondrial Hsp70s with the Escort Protein Zim17 Is Critical for Fe/S Biogenesis and Substrate Interaction at the Inner Membrane Preprotein Translocase

The yeast protein Zim17 belongs to a unique class of co-chaperones that maintain the solubility of Hsp70 proteins in mitochondria and plastids of eukaryotic cells. However, little is known about the functional cooperation between Zim17 and mitochondrial Hsp70 proteins in vivo. To analyze the effects...

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Detalhes bibliográficos
Main Authors: Lewrenz, Ilka, Rietzschel, Nicole, Guiard, Bernard, Lill, Roland, van der Laan, Martin, Voos, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829407/
https://ncbi.nlm.nih.gov/pubmed/24030826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.465997
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