The Power of Two: ARGININE 51 AND ARGININE 239* FROM A NEIGHBORING SUBUNIT ARE ESSENTIAL FOR CATALYSIS IN α-AMINO-β-CARBOXYMUCONATE-ϵ-SEMIALDEHYDE DECARBOXYLASE

Although the crystal structure of α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase from Pseudomonas fluorescens was solved as a dimer, this enzyme is a mixture of monomer, dimer, and higher order structures in solution. In this work, we found that the dimeric state, not the monomeric state, is...

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Autors principals: Huo, Lu, Davis, Ian, Chen, Lirong, Liu, Aimin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829401/
https://ncbi.nlm.nih.gov/pubmed/24019523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496869
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