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Human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling
Human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase determines the fate of tryptophan metabolites in the kynurenine pathway by controlling the quinolinate levels for de novo NAD biosynthesis. The unstable nature of its substrate has made gaining insight into its reaction mechanism difficult...
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| Publicado no: | Proteins |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289673/ https://ncbi.nlm.nih.gov/pubmed/25392945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24722 |
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