Human Ovarian Cancer Stroma Contains Luteinized Theca Cells Harboring Tumor Suppressor Gene GT198 Mutations

Ovarian cancer is a highly lethal gynecological cancer, and its causes remain to be understood. Using a recently identified tumor suppressor gene, GT198 (PSMC3IP), as a unique marker, we searched for the identity of GT198 mutant cells in ovarian cancer. GT198 has germ line mutations in familial and...

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Main Authors: Peng, Min, Zhang, Hao, Jaafar, Lahcen, Risinger, John I., Huang, Shuang, Mivechi, Nahid F., Ko, Lan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829185/
https://ncbi.nlm.nih.gov/pubmed/24097974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.485581
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