Characterization of the Translocation-competent Complex between the Helicobacter pylori Oncogenic Protein CagA and the Accessory Protein CagF

CagA is a virulence factor that Helicobacter pylori inject into gastric epithelial cells through a type IV secretion system where it can cause gastric adenocarcinoma. Translocation is dependent on the presence of secretion signals found in both the N- and C-terminal domains of CagA and an interactio...

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Main Authors: Bonsor, Daniel A., Weiss, Evelyn, Iosub-Amir, Anat, Reingewertz, Tali H., Chen, Tiffany W., Haas, Rainer, Friedler, Assaf, Fischer, Wolfgang, Sundberg, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829141/
https://ncbi.nlm.nih.gov/pubmed/24072713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507657
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