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Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization

A blockade of CD44 can interfere with haematopoietic and leukemic stem cell homing, the latter being considered as a therapeutic option in haematological malignancies. We here aimed to explore the molecular mechanism underlying the therapeutic efficacy of anti-CD44. We noted that in irradiated mice...

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Autors principals: Rajasagi, Mohini, von Au, Anja, Singh, Rahul, Hartmann, Natalie, Zöller, Margot, Marhaba, Rachid
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829012/
https://ncbi.nlm.nih.gov/pubmed/19765170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00909.x
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