Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells

Fibroblast growth factor receptor-1 (Fgfr1) gene knockout impairs cardiac and haematopoietic development in murine embryonic stem cells (mESC). In FGFR1, tyrosine residues Y653 and Y654 are responsible for its tyrosine kinase (TK) activity whereas phosphorylated Y463 and Y766 represent docking sites...

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Main Authors: Ronca, Roberto, Gualandi, Laura, Crescini, Elisabetta, Calza, Stefano, Presta, Marco, Dell’Era, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828861/
https://ncbi.nlm.nih.gov/pubmed/19549074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00805.x
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