Cell membrane GM(1) ganglioside is a functional coreceptor for fibroblast growth factor 2

Free gangliosides bind fibroblast growth factor 2 (FGF2), thus preventing cell interaction and biological activity of the growth factor in endothelial cells. Here we investigated the role of cell-associated gangliosides in mediating the biological activity of FGF2. Treatment of endothelial cells of...

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Bibliographische Detailangaben
Hauptverfasser: Rusnati, Marco, Urbinati, Chiara, Tanghetti, Elena, Dell'Era, Patrizia, Lortat-Jacob, Hugues, Presta, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123654/
https://ncbi.nlm.nih.gov/pubmed/11917140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072651899
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