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Cell membrane GM(1) ganglioside is a functional coreceptor for fibroblast growth factor 2
Free gangliosides bind fibroblast growth factor 2 (FGF2), thus preventing cell interaction and biological activity of the growth factor in endothelial cells. Here we investigated the role of cell-associated gangliosides in mediating the biological activity of FGF2. Treatment of endothelial cells of...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123654/ https://ncbi.nlm.nih.gov/pubmed/11917140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072651899 |
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