Cell membrane GM(1) ganglioside is a functional coreceptor for fibroblast growth factor 2

Free gangliosides bind fibroblast growth factor 2 (FGF2), thus preventing cell interaction and biological activity of the growth factor in endothelial cells. Here we investigated the role of cell-associated gangliosides in mediating the biological activity of FGF2. Treatment of endothelial cells of...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Rusnati, Marco, Urbinati, Chiara, Tanghetti, Elena, Dell'Era, Patrizia, Lortat-Jacob, Hugues, Presta, Marco
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917140/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072651899
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