PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease

Amyloid β-peptide (Aβ) deposits and neurofibrillary tangles are key hallmarks in Alzheimer's disease (AD). Aβ stimulates many signal transducers involved in the neuronal death. However, many mechanisms remain to be elucidated because no definitive therapy of AD exists. Some studies have focused...

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Hauptverfasser: Morel, Milena, Couturier, Julien, Lafay-Chebassier, Claire, Paccalin, Marc, Page, Guylène
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828860/
https://ncbi.nlm.nih.gov/pubmed/19602051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00849.x
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