PPARγ ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells

In human cells the length of telomeres depends on telomerase activity. This activity and the expression of the catalytic subunit of human telomerase reverse transcriptase (hTERT) is strongly up-regulated in most human cancers. hTERT expression is regulated by different transcription factors, such as...

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Hoofdauteurs: Toaldo, Cristina, Pizzimenti, Stefania, Cerbone, Angelo, Pettazzoni, Piergiorgio, Menegatti, Elisa, Daniela, Berardi, Minelli, Rosalba, Giglioni, Barbara, Dianzani, Mario Umberto, Ferretti, Carlo, Barrera, Giuseppina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828851/
https://ncbi.nlm.nih.gov/pubmed/19912441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00966.x
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