Competitive inhibition of colchicine binding to tubulin by microtubule-associated proteins.

Microtubule-associated proteins (MAPs) promote tubulin polymerization, whereas colchicine inhibits this process. In this paper, MAPs have been shown to inhibit colchicine binding to tubulin in a competitive manner. Attempts were made to identify which of the MAPs fraction(s) was responsible; both ta...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nunez, J, Fellous, A, Francon, J, Lennon, A M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1979
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/284377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.1.86
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