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FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice

Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an inherited, progressive and incurable muscle disorder. However, the molecular mechanisms underlying disease pathogenesis are not fully understood. We...

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Autori principali: Krajacic, Predrag, Pistilli, Emidio E., Tanis, Jessica E., Khurana, Tejvir S., Lamitina, S. Todd
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828772/
https://ncbi.nlm.nih.gov/pubmed/24244862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135637
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