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CLHM-1 is a Functionally Conserved and Conditionally Toxic Ca(2+)-Permeable Ion Channel in Caenorhabditis elegans

Disruption of neuronal Ca(2+) homeostasis contributes to neurodegenerative diseases through mechanisms that are not fully understood. A polymorphism in CALHM1, a recently described ion channel that regulates intracellular Ca(2+) levels, is a possible risk factor for late-onset Alzheimer's disea...

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Detalhes bibliográficos
Main Authors: Tanis, Jessica E., Ma, Zhongming, Krajacic, Predrag, He, Liping, Foskett, J. Kevin, Lamitina, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721838/
https://ncbi.nlm.nih.gov/pubmed/23884934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5919-12.2013
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