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AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling
AMPK is a serine/threonine kinase that regulates energy homeostasis and metabolic stress in eukaryotes. Previous work from our laboratory, as well as by others, has provided evidence that AMPKα1 acts as a negative regulator of TLR-induced inflammatory function. Herein, we demonstrate that AMPKα1-def...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Leukocyte Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828606/ https://ncbi.nlm.nih.gov/pubmed/23883517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0313157 |
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