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An essential role for Rab27a GTPase in eosinophil exocytosis

Eosinophil degranulation has been implicated in inflammatory processes associated with allergic asthma. Rab27a, a Rab-related GTPase, is a regulatory intracellular signaling molecule expressed in human eosinophils. We postulated that Rab27a regulates eosinophil degranulation. We investigated the rol...

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Bibliografiske detaljer
Main Authors: Kim, John Dongil, Willetts, Lian, Ochkur, Sergei, Srivastava, Nutan, Hamburg, Rudolf, Shayeganpour, Anooshirvan, Seabra, Miguel C., Lee, James J., Moqbel, Redwan, Lacy, Paige
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828600/
https://ncbi.nlm.nih.gov/pubmed/23986549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0812431
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