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Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta

Deletion of AQP1 in mice results in diminished urinary concentrating ability, possibly related to reduced NaCl- and urea gradient–driven water transport across the outer medullary descending vasa recta (OMDVR). To quantify the role of AQP1 in OMDVR water transport, we measured osmotically driven wat...

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Bibliographische Detailangaben
Hauptverfasser: Pallone, Thomas L., Edwards, Aurélie, Ma, Tonghui, Silldorff, Erik P., Verkman, A.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC382858/
https://ncbi.nlm.nih.gov/pubmed/10642600
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