Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta

Deletion of AQP1 in mice results in diminished urinary concentrating ability, possibly related to reduced NaCl- and urea gradient–driven water transport across the outer medullary descending vasa recta (OMDVR). To quantify the role of AQP1 in OMDVR water transport, we measured osmotically driven wat...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Pallone, Thomas L., Edwards, Aurélie, Ma, Tonghui, Silldorff, Erik P., Verkman, A.S.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 2000
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10642600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8214
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