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Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression
More than half of human genes use alternative cleavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the lengths of their 3′ untranslated regions (UTRs), thus altering the post-transcriptional fate of the message and likely the protein output. The extent of 3′ UTR variation a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828523/ https://ncbi.nlm.nih.gov/pubmed/24145798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.229328.113 |
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