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Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

More than half of human genes use alternative cleavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the lengths of their 3′ untranslated regions (UTRs), thus altering the post-transcriptional fate of the message and likely the protein output. The extent of 3′ UTR variation a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lianoglou, Steve, Garg, Vidur, Yang, Julie L., Leslie, Christina S., Mayr, Christine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828523/
https://ncbi.nlm.nih.gov/pubmed/24145798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.229328.113
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