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Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

More than half of human genes use alternative cleavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the lengths of their 3′ untranslated regions (UTRs), thus altering the post-transcriptional fate of the message and likely the protein output. The extent of 3′ UTR variation a...

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Detalhes bibliográficos
Main Authors: Lianoglou, Steve, Garg, Vidur, Yang, Julie L., Leslie, Christina S., Mayr, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828523/
https://ncbi.nlm.nih.gov/pubmed/24145798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.229328.113
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