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Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates

The stereotyped arrangement of cochlear sensory and supporting cells is critical for auditory function. Our previous studies showed that Muenke syndrome model mice (Fgfr3(P244R/+)) have hearing loss associated with a supporting cell fate transformation of two Deiters' cells to two pillar cells....

Deskribapen osoa

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Xehetasun bibliografikoak
Egile Nagusiak: Mansour, Suzanne L., Li, Chaoying, Urness, Lisa D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828518/
https://ncbi.nlm.nih.gov/pubmed/24145799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.228957.113
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