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Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates
The stereotyped arrangement of cochlear sensory and supporting cells is critical for auditory function. Our previous studies showed that Muenke syndrome model mice (Fgfr3(P244R/+)) have hearing loss associated with a supporting cell fate transformation of two Deiters' cells to two pillar cells....
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828518/ https://ncbi.nlm.nih.gov/pubmed/24145799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.228957.113 |
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