KSRP Modulation of GAP-43 mRNA Stability Restricts Axonal Outgrowth in Embryonic Hippocampal Neurons

The KH-type splicing regulatory protein (KSRP) promotes the decay of AU-rich element (ARE)-containing mRNAs. Although KSRP is expressed in the nervous system, very little is known about its role in neurons. In this study, we examined whether KSRP regulates the stability of the ARE-containing GAP-43...

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Auteurs principaux: Bird, Clark W., Gardiner, Amy S., Bolognani, Federico, Tanner, Daniel C., Chen, Ching-Yi, Lin, Wei-Jye, Yoo, Soonmoon, Twiss, Jeffery L., Perrone- Bizzozero, Nora
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828348/
https://ncbi.nlm.nih.gov/pubmed/24244461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079255
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