KSRP Modulation of GAP-43 mRNA Stability Restricts Axonal Outgrowth in Embryonic Hippocampal Neurons

The KH-type splicing regulatory protein (KSRP) promotes the decay of AU-rich element (ARE)-containing mRNAs. Although KSRP is expressed in the nervous system, very little is known about its role in neurons. In this study, we examined whether KSRP regulates the stability of the ARE-containing GAP-43...

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Autors principals: Bird, Clark W., Gardiner, Amy S., Bolognani, Federico, Tanner, Daniel C., Chen, Ching-Yi, Lin, Wei-Jye, Yoo, Soonmoon, Twiss, Jeffery L., Perrone- Bizzozero, Nora
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828348/
https://ncbi.nlm.nih.gov/pubmed/24244461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079255
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