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The Development of an Experimental Multiple Serogroups Vaccine for Neisseria meningitidis

A native outer membrane vesicles (NOMV) vaccine was developed from three antigenically diverse strains of Neisseria meningitidis that express the L1,8, L2, and L3,7 lipooligosaccharide (LOS) immunotypes, and whose synX, and lpxL1 genes were deleted.. Immunogenicity studies in mice showed that the va...

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Autors principals: Pinto, Valerian B., Burden, Robert, Wagner, Allyn, Moran, Elizabeth E., Lee, Che-Hung
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828347/
https://ncbi.nlm.nih.gov/pubmed/24244473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079304
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