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The Development of an Experimental Multiple Serogroups Vaccine for Neisseria meningitidis

A native outer membrane vesicles (NOMV) vaccine was developed from three antigenically diverse strains of Neisseria meningitidis that express the L1,8, L2, and L3,7 lipooligosaccharide (LOS) immunotypes, and whose synX, and lpxL1 genes were deleted.. Immunogenicity studies in mice showed that the va...

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Detalhes bibliográficos
Main Authors: Pinto, Valerian B., Burden, Robert, Wagner, Allyn, Moran, Elizabeth E., Lee, Che-Hung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828347/
https://ncbi.nlm.nih.gov/pubmed/24244473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079304
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