Regulation of Mycolactone, the Mycobacterium ulcerans Toxin, Depends on Nutrient Source

BACKGROUND: Mycobacterium ulcerans, a slow-growing environmental bacterium, is the etiologic agent of Buruli ulcer, a necrotic skin disease. Skin lesions are caused by mycolactone, the main virulence factor of M. ulcerans, with dermonecrotic (destruction of the skin and soft tissues) and immunosuppr...

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Autors principals: Deshayes, Caroline, Angala, Shiva Kumar, Marion, Estelle, Brandli, Irène, Babonneau, Jérémie, Preisser, Laurent, Eyangoh, Sara, Delneste, Yves, Legras, Pierre, De Chastellier, Chantal, Stinear, Timothy P., Jackson, Mary, Marsollier, Laurent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828164/
https://ncbi.nlm.nih.gov/pubmed/24244764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002502
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