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Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

Mycolactone is a polyketide toxin produced by Mycobacterium ulcerans (Mu), the causative agent of the skin disease Buruli ulcer (BU). Surprisingly, infected tissues lack inflammatory infiltrates. Structural similarities between mycolactone and immunosuppressive agents led us to investigate the immun...

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Detalhes bibliográficos
Main Authors: Coutanceau, Emmanuelle, Decalf, Jeremie, Martino, Angelo, Babon, Aurélie, Winter, Nathalie, Cole, Stewart T., Albert, Matthew L., Demangel, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118602/
https://ncbi.nlm.nih.gov/pubmed/17517970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070234
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