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Murine AIDS requires CD154/CD40L expression by the CD4 T cells that mediate retrovirus-induced disease: Is CD4 T cell receptor ligation needed?

LP-BM5, a retroviral isolate, induces a disease featuring an acquired immunodeficiency syndrome termed murine AIDS (MAIDS). Many of the features of the LP-BM5-initiated disease are shared with HIV/AIDS. Our lab has shown that the interaction of B and CD4 T cells that is central to MAIDS pathogenesis...

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Bibliografske podrobnosti
Main Authors: Li, Wen, Green, William R.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827965/
https://ncbi.nlm.nih.gov/pubmed/17113120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.10.002
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