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Increased TORC2 signaling promotes age-related decline in CD4 T cell signaling and function
CD4 T cell function declines significantly during aging. While the mammalian target of rapamycin (TOR) has been implicated in aging, the roles of the TOR complexes (TORC1, TORC2) in the functional declines of CD4 T cells remain unknown. In this study, we demonstrate that aging increases TORC2 signal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827688/ https://ncbi.nlm.nih.gov/pubmed/24078700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300750 |
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