Genetic Deletion of Afadin Causes Hydrocephalus by Destruction of Adherens Junctions in Radial Glial and Ependymal Cells in the Midbrain

Adherens junctions (AJs) play a role in mechanically connecting adjacent cells to maintain tissue structure, particularly in epithelial cells. The major cell–cell adhesion molecules at AJs are cadherins and nectins. Afadin binds to both nectins and α-catenin and recruits the cadherin-β-catenin compl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamamoto, Hideaki, Maruo, Tomohiko, Majima, Takashi, Ishizaki, Hiroyoshi, Tanaka-Okamoto, Miki, Miyoshi, Jun, Mandai, Kenji, Takai, Yoshimi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827428/
https://ncbi.nlm.nih.gov/pubmed/24236178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080356
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