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Afadin Regulates Puncta Adherentia Junction Formation and Presynaptic Differentiation in Hippocampal Neurons

The formation and remodeling of mossy fiber-CA3 pyramidal cell synapses in the stratum lucidum of the hippocampus are implicated in the cellular basis of learning and memory. Afadin and its binding cell adhesion molecules, nectin-1 and nectin-3, together with N-cadherin, are concentrated at puncta a...

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Detalhes bibliográficos
Main Authors: Toyoshima, Daisaku, Mandai, Kenji, Maruo, Tomohiko, Supriyanto, Irwan, Togashi, Hideru, Inoue, Takahito, Mori, Masahiro, Takai, Yoshimi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937348/
https://ncbi.nlm.nih.gov/pubmed/24587018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089763
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