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Denatured State Structural Property Determines Protein Stabilization by Macromolecular Crowding: A Thermodynamic and Structural Approach
Understanding of protein structure and stability gained to date has been acquired through investigations made under dilute conditions where total macromolecular concentration never surpasses 10 g l(−1). However, biological macromolecules are known to evolve and function under crowded intracellular e...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827121/ https://ncbi.nlm.nih.gov/pubmed/24265729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078936 |
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