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Denatured State Structural Property Determines Protein Stabilization by Macromolecular Crowding: A Thermodynamic and Structural Approach

Understanding of protein structure and stability gained to date has been acquired through investigations made under dilute conditions where total macromolecular concentration never surpasses 10 g l(−1). However, biological macromolecules are known to evolve and function under crowded intracellular e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mittal, Shruti, Singh, Laishram Rajendrakumar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827121/
https://ncbi.nlm.nih.gov/pubmed/24265729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078936
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