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Drosophila UTX Coordinates with p53 to Regulate ku80 Expression in Response to DNA Damage

UTX is known as a general factor that activates gene transcription during development. Here, we demonstrate an additional essential role of UTX in the DNA damage response, in which it upregulates the expression of ku80 in Drosophila, both in cultured cells and in third instar larvae. We further show...

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Bibliografske podrobnosti
Main Authors: Zhang, Chengwan, Hong, Zehui, Ma, Wencui, Ma, Da, Qian, Yuchen, Xie, Wei, Tie, Feng, Fang, Ming
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827076/
https://ncbi.nlm.nih.gov/pubmed/24265704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078652
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