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LC/ESI-MS/MS detection of FAs by charge reversal derivatization with more than four orders of magnitude improvement in sensitivity

Quantitative analysis of fatty acids (FAs) is an important area of analytical biochemistry. Ultra high sensitivity FA analysis usually is done with gas chromatography of pentafluorobenzyl esters coupled to an electron-capture detector. With the popularity of electrospray ionization (ESI) mass spectr...

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Detalhes bibliográficos
Main Authors: Bollinger, James G., Rohan, Gajendra, Sadilek, Martin, Gelb, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826698/
https://ncbi.nlm.nih.gov/pubmed/23945566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D040782
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