Improved Sensitivity Mass Spectrometric Detection of Eicosanoids by Charge Reversal Derivatization

Combined liquid chromatography–electrospray ionization-tandem mass spectrometry (LC–ESI-MS/MS) is a powerful method for the analysis of oxygenated metabolites of polyunsaturated fatty acids including eicosanoids. Here we describe the synthesis of a new derivatization reagent N-(4-aminomethylphenyl)p...

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Autori principali: Bollinger, James G., Thompson, Wallace, Lai, Ying, Oslund, Rob C., Hallstrand, Teal S., Sadilek, Martin, Turecek, Frantisek, Gelb, Michael H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959116/
https://ncbi.nlm.nih.gov/pubmed/20704368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac100720p
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