A mechanism for suppression of the CDP-choline pathway during apoptosis

Inhibition of the CDP-choline pathway during apoptosis restricts the availability of phosphatidylcholine (PtdCho) for assembly of membranes and synthesis of signaling factors. The N-terminal nuclear localization signal (NLS) in CTP:phosphocholine cytidylyltransferase (CCT)α is removed during apoptos...

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Autors principals: Morton, Craig C., Aitchison, Adam J., Gehrig, Karsten, Ridgway, Neale D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826684/
https://ncbi.nlm.nih.gov/pubmed/24136823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M041434
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