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Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain
CTP:phosphocholine cytidylyltransferase α (CCTα), the rate-limiting enzyme in the CDP-choline pathway for phosphatidylcholine (PtdCho) synthesis, is activated by translocation to nuclear membranes. However, CCTα is cytoplasmic in cells with increased capacity for PtdCho synthesis and following acute...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666183/ https://ncbi.nlm.nih.gov/pubmed/19098306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800632-JLR200 |
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