Rapamycin has suppressive and stimulatory effects on human plasmacytoid dendritic cell functions

Plasmacytoid dendritic cells (PDC) are involved in innate immunity by interferon (IFN)-α production, and in adaptive immunity by stimulating T cells and inducing generation of regulatory T cells (T(reg)). In this study we studied the effects of mammalian target of rapamycin (mTOR) inhibition by rapa...

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Hlavní autoři: Boor, P P C, Metselaar, H J, Mancham, S, van der Laan, L J W, Kwekkeboom, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2013
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826305/
https://ncbi.nlm.nih.gov/pubmed/23968562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12191
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