Syndecan-2 Exerts Antifibrotic Effects by Promoting Caveolin-1–mediated Transforming Growth Factor-β Receptor I Internalization and Inhibiting Transforming Growth Factor-β1 Signaling

Rationale: Alveolar transforming growth factor (TGF)-β1 signaling and expression of TGF-β1 target genes are increased in patients with idiopathic pulmonary fibrosis (IPF) and in animal models of pulmonary fibrosis. Internalization and degradation of TGF-β receptor TβRI inhibits TGF-β signaling and c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shi, Yuanyuan, Gochuico, Bernadette R., Yu, Guoying, Tang, Xiaomeng, Osorio, Juan C., Fernandez, Isis E., Risquez, Cristobal F., Patel, Avignat S., Shi, Ying, Wathelet, Marc G., Goodwin, Andrew J., Haspel, Jeffrey A., Ryter, Stefan W., Billings, Eric M., Kaminski, Naftali, Morse, Danielle, Rosas, Ivan O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826270/
https://ncbi.nlm.nih.gov/pubmed/23924348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201303-0434OC
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados