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Crystal structure of human seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes
Seryl-tRNA synthetase (SerRS), an essential enzyme for translation, also regulates vascular development. This “gain-of-function” has been linked to the UNE-S domain added to vertebrate SerRS during evolution. However, the significance of two insertions also specific to higher eukaryotic SerRS remain...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825832/ https://ncbi.nlm.nih.gov/pubmed/24095058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.021 |
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