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Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery

The bioavailability of paclitaxel (Ptx) has previously been improved via its encapsulation in lipid nanocapsules (LNCs). In this work, the interactions between LNCs and intestinal mucus are studied because they are viewed as an important barrier to successful oral delivery. The rheological propertie...

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Bibliografische gegevens
Hoofdauteurs: Groo, Anne-Claire, Saulnier, Patrick, Gimel, Jean-Christophe, Gravier, Julien, Ailhas, Caroline, Benoit, Jean-Pierre, Lagarce, Frederic
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825687/
https://ncbi.nlm.nih.gov/pubmed/24235827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51837
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